Immune Regulatory Genes Are Major Genetic Factors to Behcet Disease: Systematic Review

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Immunology of Behcet disease: review article

Behçet's disease (BD), also known as the Silk Road disease, is a multisystemic and rare inflammatory disorder primarily prevalent in populations along the Mediterranean Sea. Today, BD is defined as a crossroad between autoimmune and auto-inflammatory syndromes. Variety of syndromes including mucocutaneous manifestations such as oral and genital ulcers, papulopustular lesions and erythema nodosu...

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[Behcet disease].

Central nervous system involvement in Behçet disease (BD) may be either parenchymal or nonparenchymal. Abnormal cerebrospinal fluid findings and parenchymal involvement are associated with a poorer prognosis. A self-antigenic role for HLA B51 has been postulated in the pathogenesis of BD. The sibling occurrence rate is 3.6%. Familial aggregation may be more pronounced among pediatric cases comp...

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ژورنال

عنوان ژورنال: The Open Rheumatology Journal

سال: 2018

ISSN: 1874-3129

DOI: 10.2174/1874312901812010070